LC-11 (HUNT B,JONES) AS A MUTUALLY EXCLUSIVE SPECIFICITY TO LC-1,2, AND 3 IN MAIN HUMAN LEUKOCYTE GROUP

被引:18
作者
WALFORD, RL
WALLACE, O
SHANBROM, E
TROUP, GM
机构
[1] Department of Pathology, University of California School of Medicine, Los Angeles, Research Division of Hyland Laboratories, Los Angeles, California
关键词
D O I
10.1111/j.1423-0410.1968.tb04074.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Summary. The specificity Lc‐11, defined by properly adsorbed Hunt serum (Hunt B), or by the monospecific serum Jones, reveals a completely mutually exclusive relationship to Lc‐1, 2, and 3 of the main (HL‐A) leukocyte group, when tested against 290 random Caucasian donors and 56 negro donors. Jones antiserum was produced by planned immunization directed towards producing a specificity of this nature. A structural relationship of the various human leukocyte factors is proposed which is strictly analogous to the Rh system in man or the B blood group system in cattle. A number of criteria are set forth, the fulfillment of which would reinforce this interpretation. © 1968 Blackwell Publishing Ltd
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页码:338 / &
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