Evaluation of the antifertility activity of the broom Spartium junceum in the mammalian male

被引:6
|
作者
Baccetti, B. [1 ,2 ]
Burrini, A. G.
Chen, J. S.
Collodel, G.
Giachetti, D.
Matteucci, F.
Menesini-Chen, M. G.
Moretti, E.
Piomboni, P.
Sensini, C.
机构
[1] CNR, Ist Biol Gen, I-53100 Siena, Italy
[2] CNR, Ctr Studio Cellule Germinali, I-53100 Siena, Italy
关键词
Acrosome; Contraception; Rabbit; Rat; Spartium junceum;
D O I
10.1017/S0967199400001313
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Male adult rabbits and rats treated with Spartium junceum showed a significant decrease in fertility, demonstrated by a lower number of pregnancies. The target of the drug seems to be the acrosomal protease system, the activity of which appears greatly reduced, while the morphology of testicular cells and epididymal spermatozoa is only partially affected. The antifertility effect is completely reversible.
引用
收藏
页码:71 / 78
页数:8
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