Evaluation of the antifertility activity of the broom Spartium junceum in the mammalian male

被引：6
作者：
Baccetti, B. [1 ,2 ]
Burrini, A. G.
Chen, J. S.
Collodel, G.
Giachetti, D.
Matteucci, F.
Menesini-Chen, M. G.
Moretti, E.
Piomboni, P.
Sensini, C.
机构：
[1] CNR, Ist Biol Gen, I-53100 Siena, Italy
[2] CNR, Ctr Studio Cellule Germinali, I-53100 Siena, Italy
来源：
ZYGOTE | 1993年 / 1卷 / 01期
关键词：
Acrosome; Contraception; Rabbit; Rat; Spartium junceum;
D O I：
10.1017/S0967199400001313
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Male adult rabbits and rats treated with Spartium junceum showed a significant decrease in fertility, demonstrated by a lower number of pregnancies. The target of the drug seems to be the acrosomal protease system, the activity of which appears greatly reduced, while the morphology of testicular cells and epididymal spermatozoa is only partially affected. The antifertility effect is completely reversible.
引用
收藏
页码：71 / 78
页数：8
相关论文
共 13 条
  • [1] Bhargava S.K., 1987, FITOTERAPIA, V59, P163
  • [2] Bingel A.S., 1988, EC MED PLANT RES, V2, P73
  • [3] Chen J.S., 1991, COMP SPERMATOLOGY 20, V75, P125
  • [4] Giachetti D., 1991, COMP SPERMATOLOGY 20, V75, P829
  • [5] *INT FED CLIN CHEM, 1980, CLIN CHIM ACTA, V105, pF147
  • [6] KONG YC, 1986, J ETHNOPHARMACOL, V15, P1, DOI 10.1016/0378-8741(86)90102-9
  • [7] LOWRY OH, 1951, J BIOL CHEM, V193, P265
  • [8] Lurz G., 1990, P INT JOINT S BIOL C, P33
  • [9] Waller D.P., 1985, EC MED PLANT RES, V1, P87
  • [10] PLANTS OF HAITI USED AS ANTIFERTILITY AGENTS
    WENIGER, B
    HAAGBERRURIER, M
    ANTON, R
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 1982, 6 (01) : 67 - 84
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