Betablockers in patients with heart failure and atrial fibrillation

被引:1
作者
Pellicori, Pierpaolo [1 ]
Costanzo, Pierluigi [1 ]
机构
[1] Univ Hull, Castle Hill Hosp, Hull York Med Sch, Acad Cardiol Unit, Cottingham HU16 5JQ, England
关键词
Atrial fibrillation; Beta-blockers; Heart failure;
D O I
10.1714/2066.22428
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A recent individual patient data meta-analysis has shown that beta-blockers reduce mortality in patients with heart failure and reduced left ventricular ejection fraction (HFrEF) who are in sinus rhythm but not in those who are in atrial fibrillation. Similar results applied also to cardiovascular death or first hospitalization for heart failure. The European Society of Cardiology guidelines recommend beta-blockers in patients with HFrEF regardless of baseline rhythm. However, despite improving symptoms, the prognostic benefits of beta-blockers have now been questioned by these authors in patients with HFrEF and atrial fibrillation. In this review we comment the findings of this study.
引用
收藏
页码:613 / 616
页数:4
相关论文
共 31 条
[1]   MAXIMAL EXERCISE TESTING AND GAS-EXCHANGE IN PATIENTS WITH CHRONIC ATRIAL-FIBRILLATION [J].
ATWOOD, JE ;
MYERS, J ;
SULLIVAN, M ;
FORBES, S ;
FRIIS, R ;
PEWEN, W ;
CALLAHAM, P ;
HALL, P ;
FROELICHER, V .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1988, 11 (03) :508-513
[2]   Association of Heart Rate and Outcomes in a Broad Spectrum of Patients With Chronic Heart Failure [J].
Castagno, Davide ;
Skali, Hicham ;
Takeuchi, Madoka ;
Swedberg, Karl ;
Yusuf, Salim ;
Granger, Christopher B. ;
Michelson, Eric L. ;
Pfeffer, Marc A. ;
McMurray, John J. V. ;
Solomon, Scott D. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 59 (20) :1785-+
[3]   Hemodynamic effects of an irregular sequence of ventricular cycle lengths during atrial fibrillation [J].
Clark, DM ;
Plumb, VJ ;
Epstein, AE ;
Kay, GN .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (04) :1039-1045
[4]   Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial [J].
Dargie, HJ ;
Colucci, Y ;
Ford, I ;
Sendon, JLL ;
Remme, W ;
Sharpe, N ;
Blank, A ;
Holcslaw, TL .
LANCET, 2001, 357 (9266) :1385-1390
[5]   Prescribing Patterns to Optimize Heart Rate Analysis of 1,000 Consecutive Outpatient Appointments to a Single Heart Failure Clinic Over a 6-Month Period [J].
Dierckx, Riet ;
Cleland, John G. F. ;
Parsons, Sunaina ;
Putzu, Paola ;
Pellicori, Pierpaolo ;
Dicken, Benjamin ;
Boyalla, Vennela ;
Clark, Andrew L. .
JACC-HEART FAILURE, 2015, 3 (03) :224-230
[6]  
Eichhorn E, 2001, NEW ENGL J MED, V344, P1659
[7]   FASTTRACK Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS) [J].
Flather, MD ;
Shibata, MC ;
Coats, AJS ;
Van Veldhuisen, DJ ;
Parkhomenko, A ;
Borbola, J ;
Cohen-Solal, A ;
Dumitrascu, D ;
Ferrari, R ;
Lechat, P ;
Soler-Soler, J ;
Tavazzi, L ;
Spinarova, L ;
Toman, J ;
Böhm, M ;
Anker, SD ;
Thompson, SG ;
Poole-Wilson, PA .
EUROPEAN HEART JOURNAL, 2005, 26 (03) :215-225
[8]   Digoxin and Risk of Death in Adults With Atrial Fibrillation The ATRIA-CVRN Study [J].
Freeman, James V. ;
Reynolds, Kristi ;
Fang, Margaret ;
Udaltsova, Natalia ;
Steimle, Anthony ;
Pomernacki, Niela K. ;
Borowsky, Leila H. ;
Harrison, Teresa N. ;
Singer, Daniel E. ;
Go, Alan S. .
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2015, 8 (01) :49-U77
[9]   Digoxin in atrial fibrillation: report from the Stockholm Cohort study of Atrial Fibrillation (SCAF) [J].
Friberg, L. ;
Hammar, N. ;
Rosenqvist, M. .
HEART, 2010, 96 (04) :275-280
[10]   Lack of evidence of increased mortality among patients with atrial fibrillation taking digoxin: findings from post hoc propensity-matched analysis of the AFFIRM trial [J].
Gheorghiade, Mihai ;
Fonarow, Gregg C. ;
van Veldhuisen, Dirk J. ;
Cleland, John G. F. ;
Butler, Javed ;
Epstein, Andrew E. ;
Patel, Kanan ;
Aban, Inmaculada B. ;
Aronow, Wilbert S. ;
Anker, Stefan D. ;
Ahmed, Ali .
EUROPEAN HEART JOURNAL, 2013, 34 (20) :1489-+