GLIOMATOSIS CEREBRI - THE DIAGNOSTIC POTENTIAL OF MRI

Gliomatosis cerebri is a rare tumor of neuroepithelial origin in middle aged persons presented by deterioration of cognitive functions, psychomotor retardation and cerebral convulsions. MRI predominantly shows a bilateral and diffuse infiltration of midline adjacent brain structures including medulla. Areas with focal anaplasia occasionally reveal an accumulation of contrast media. The diffuse tumor manifestation requires a differentiation from encephalitis and demyelinating diseases with a similar distribution pattern of lesions. Three cases have been examined. In conclusion the performance of MRI including control and brain biopsy are indicated to establish an in vivo diagnosis.