PLASMID INCIDENCE RATE AND CONJUGATIVE CHLORAMPHENICOL AND TETRACYCLINE RESISTANCE PLASMIDS IN MALAYSIAN ISOLATES OF SALMONELLA-TYPHI

被引：13
作者：
PHIPPS, M
PANG, T
KOH, CL
PUTHUCHEARY, S
机构：
[1] UNIV MALAYA,INST ADV STUDIES,KUALA LUMPUR 59100,MALAYSIA
[2] UNIV MALAYA,DEPT GENET & CELLULAR BIOL,KUALA LUMPUR 59100,MALAYSIA
[3] UNIV MALAYA,DEPT MED MICROBIOL,KUALA LUMPUR 59100,MALAYSIA
来源：
MICROBIOLOGY AND IMMUNOLOGY | 1991年 / 35卷 / 02期
关键词：
D O I：
10.1111/j.1348-0421.1991.tb01543.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Seven (6.1%) of 115 strains of Salmonella typhi isolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid-bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coli K12 at frequencies from 1.6 x 10(-7) to 1.9 x 10(-6). Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.
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页码：157 / 161
页数：5
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