GLUTAMATE-LIKE IMMUNOREACTIVITY IN NEURONS OF THE LATERODORSAL TEGMENTAL AND PEDUNCULOPONTINE NUCLEI IN THE RAT

被引：170
作者：
CLEMENTS, JR
GRANT, S
机构：
[1] UNIV DELAWARE,DEPT PSYCHOL,220 WOLF HALL,NEWARK,DE 19716
[2] UNIV DELAWARE,SCH LIFE & HLTH SCI,NEWARK,DE 19716
来源：
NEUROSCIENCE LETTERS | 1990年 / 120卷 / 01期
关键词：
Acetylcholine; Glutamate; Immunocytochemistry; Laterodorsal tegmental nucleus; Parkinson's disease; Pedunculopontine nucleus; Reticular nuclei;
D O I：
10.1016/0304-3940(90)90170-E
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Studies of the pedunculopontine (PPT) and laterodorsal tegmental (LDT) nuclei in the mesopontine tegmentum have emphasized the organization and projections of the cholinergic neurons. We report here that exhibiting glutamate immunoreactivity are present in both the LDT and PPT. These glutamatergic neurons are interspersed among the cholinergic neurons within both nuclei with no apparent segregation. These data raise the possibility that excitatory amino acids contribute to the functions of the LDT and PPT. © 1990.
引用
收藏
页码：70 / 73
页数：4
相关论文
共 29 条
[1]   A CHOLINERGIC PROJECTION TO THE RAT SUBSTANTIA-NIGRA FROM THE PEDUNCULOPONTINE TEGMENTAL NUCLEUS [J].
BENINATO, M ;
SPENCER, RF .
BRAIN RESEARCH, 1987, 412 (01) :169-174
[2]   INNERVATION OF SUBSTANTIA NIGRA NEURONS BY CHOLINERGIC AFFERENTS FROM PEDUNCULOPONTINE NUCLEUS IN THE RAT - NEUROANATOMICAL AND ELECTROPHYSIOLOGICAL EVIDENCE [J].
CLARKE, PBS ;
HOMMER, DW ;
PERT, A ;
SKIRBOLL, LR .
NEUROSCIENCE, 1987, 23 (03) :1011-1019
[3]  
CLEMENTS JR, IN PRESS J ELECTRON
[4]  
CLEMENTS JR, 1990, IN PRESS SOC NEUR AB, V16
[5]   BEHAVIORAL INVESTIGATION OF THE COEXISTENCE OF SUBSTANCE-P, CORTICOTROPIN RELEASING-FACTOR, AND ACETYLCHOLINESTERASE IN LATERAL DORSAL TEGMENTAL NEURONS PROJECTING TO THE MEDIAL FRONTAL-CORTEX OF THE RAT [J].
CRAWLEY, JN ;
OLSCHOWKA, JA ;
DIZ, DI ;
JACOBOWITZ, DM .
PEPTIDES, 1985, 6 (05) :891-901
[6]   GABAERGIC BASAL FOREBRAIN NEURONS PROJECT TO THE NEOCORTEX - THE LOCALIZATION OF GLUTAMIC-ACID DECARBOXYLASE AND CHOLINE-ACETYLTRANSFERASE IN FELINE CORTICOPETAL NEURONS [J].
FISHER, RS ;
BUCHWALD, NA ;
HULL, CD ;
LEVINE, MS .
JOURNAL OF COMPARATIVE NEUROLOGY, 1988, 272 (04) :489-502
[7]   LOCOMOTION-INDUCING SITES IN THE VICINITY OF THE PEDUNCULOPONTINE NUCLEUS [J].
GARCIARILL, E ;
HOUSER, CR ;
SKINNER, RD ;
SMITH, W ;
WOODWARD, DJ .
BRAIN RESEARCH BULLETIN, 1987, 18 (06) :731-738
[8]   SEPARATE NON-CHOLINERGIC DESCENDING PROJECTIONS AND CHOLINERGIC ASCENDING PROJECTIONS FROM THE NUCLEUS TEGMENTI PEDUNCULOPONTINUS [J].
GOLDSMITH, M ;
VANDERKOOY, D .
BRAIN RESEARCH, 1988, 445 (02) :386-391
[9]   CHOLINERGIC PROJECTIONS TO THE SUBSTANTIA NIGRA FROM THE PEDUNCULOPONTINE AND LATERODORSAL TEGMENTAL NUCLEI [J].
GOULD, E ;
WOOLF, NJ ;
BUTCHER, LL .
NEUROSCIENCE, 1989, 28 (03) :611-623
[10]   USE OF AVIDIN-BIOTIN-PEROXIDASE COMPLEX (ABC) IN IMMUNOPEROXIDASE TECHNIQUES - A COMPARISON BETWEEN ABC AND UNLABELED ANTIBODY (PAP) PROCEDURES [J].
HSU, SM ;
RAINE, L ;
FANGER, H .
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1981, 29 (04) :577-580
123