TREATMENT OF CYTOMEGALOVIRUS RETINITIS WITH INTRAVITREAL INJECTION OF LIPOSOME-ENCAPSULATED GANCICLOVIR IN A PATIENT WITH AIDS

被引：43

作者：

AKULA, SK

MA, PE

PEYMAN, GA

RAHIMY, MH

HYSLOP, NE

JANNEY, A

ASHTON, P

机构：

[1] LOUISIANA STATE UNIV,CTR EYE,NEW ORLEANS,LA 70112

[2] TULANE UNIV,MED CTR,DEPT MED,NEW ORLEANS,LA 70112

[3] UNIV KENTUCKY,DEPT OPHTHALMOL,LEXINGTON,KY

[4] MED CTR LOUISIANA,DEPT MICROBIOL,NEW ORLEANS,LA

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 1994年 / 78卷 / 09期

关键词：

D O I：

10.1136/bjo.78.9.677

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

To study its safety and efficacy in treating cytomegalovirus (CMV) retinitis, an AIDS patient received an intravitreal injection of liposome encapsulated ganciclovir in the right eye. The left eye served as a control, receiving intravitreal free ganciclovir. The right eye showed no retinal haemorrhages or detachment; however, vision declined initially, stabilising later. Weekly examination showed neither progression of the CMV retinitis nor new lesions in the right eye. The left eye showed reactivation of old CMV retinitis. Liposome encapsulated ganciclovir reduced the number of intravitreal injections, stabilising CMV retinitis, and warrants further study.

引用

页码：677 / 680

页数：4

共 21 条

[1]

ACEVESCASILLAS P, 1989, AM J MED, V86, P780

[2]

Alghadyan A., 1988, AFRO ASIAN J OPHTHAL, V7, P43

[3]

BUCHI ER, 1988, ARCH OPHTHALMOL-CHIC, V106, P1349

[4] TREATMENT OF CYTOMEGALO-VIRUS RETINITIS WITH INTRAVITREAL GANCICLOVIR - LONG-TERM RESULTS [J].