DIASTEREOSELECTIVE ALDOL REACTIONS OF 2,6-DIMETHYLCYCLOHEXENONE LITHIUM ENOLATE

被引：6

作者：

MATEOS, AF

COCA, GP

ALONSO, JJP

GONZALEZ, RR

HERNANDEZ, CT

机构：

[1] Departamento de Química Orgánica, Facultad de C. Químicas, 37008 Salamanca

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 06期

关键词：

D O I：

10.1016/0040-4039(94)02401-V

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The lithium enolate of 2.6-dimethylcyclohexenone undergoes a threo selective aldol reaction with aromatic aldehydes and and 3-furaldehyde superior to saturated 2,6-dimethylcyclohexanone and 2,2,6-trimethylcyclohexanone. A stereoelectronic factor is invoked as responsible.

引用

页码：961 / 964

页数：4

共 12 条

[1]

CIEPLAK AS, 1981, J AM CHEM SOC, V103, P4540, DOI 10.1021/ja00405a041

[2]

EVANS DA, 1987, ANGEW CHEM INT EDIT, V27, P1187

[3]

EVANS DA, 1983, TOP STEREOCHEM, V13, P1

[4] DIASTEREOSELECTIVITY IN THE REDUCTION OF STERICALLY UNBIASED 2,2-DIARYLCYCLOPENTANONES [J].