GENETIC BASIS FOR UNRESPONSIVENESS TO LIPOPOLYSACCHARIDE IN C57BL-10CR MICE

被引：120

作者：

COUTINHO, A

MEO, T

机构：

[1] Basel Institute for Immunology, Basel 5

来源：

IMMUNOGENETICS | 1978年 / 7卷 / 01期

关键词：

D O I：

10.1007/BF01843983

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The unresponsiveness to LPS detected in C57BL/10Cr mice is inherited as a recessive trait and is determined by an autosomal gene linked to the Mup-1 locus on chromosome 4. Since no complementation for LPS responsiveness was observed in F1 hybrid mice between C3H/HeJ and C57BL/10Cr, we conclude that C57BL/10Cr mice carry a defective allele at the same Lps locus, previously identified by the mutation detected in the C3H/HeJ strain. © 1978 Springer-Verlag New York Inc.

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页码：17 / 24

页数：8

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