ALPHA-ADRENOCEPTOR GENE-EXPRESSION IN THE RAT IRIS DURING DEVELOPMENT AND MATURITY

被引：18
作者：
VIDOVIC, M
HILL, CE
机构：
[1] Division of Neuroscience, The John Curtin School of Medical Research, The Australian National University, Canberra
来源：
DEVELOPMENTAL BRAIN RESEARCH | 1995年 / 89卷 / 02期
关键词：
ALPHA ADRENOCEPTOR; SYMPATHETIC NEURON; IRIS; REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION; DEVELOPMENT; AGING;
D O I：
10.1016/0165-3806(95)00118-W
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We have examined the developmental profile of the alpha-1 and alpha-2 adrenergic receptor mRNA expression in the rat iris. The expression of the six mRNAs was studied using reverse transcription-polymerase chain reaction. At 4 weeks, the dominant mRNA transcripts in the rat iris were alpha-1B, alpha-1C and alpha-2A. This pattern of alpha adrenoceptor expression was seen from birth, throughout development, and maintained into old age.
引用
收藏
页码：309 / 313
页数：5
相关论文
共 32 条
[1]   DIFFERENTIAL EXPRESSION OF THE ALPHA-1C ADRENERGIC-RECEPTOR SUBTYPE IN RAT-TISSUES [J].
ALONSOLLAMAZARES, A ;
ZAMANILLO, D ;
FERNANDEZ, A ;
CHINCHETRU, MA ;
CALVO, P .
NEUROREPORT, 1993, 4 (11) :1266-1268
[2]  
BYLUND DB, 1994, PHARMACOL REV, V46, P121
[3]  
CHALBERG SC, 1990, MOL CELL BIOCHEM, V97, P161
[4]   MOLECULAR-CLONING AND EXPRESSION OF THE CDNA FOR THE HAMSTER ALPHA-1-ADRENERGIC RECEPTOR [J].
COTECCHIA, S ;
SCHWINN, DA ;
RANDALL, RR ;
LEFKOWITZ, RJ ;
CARON, MG ;
KOBILKA, BK .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (19) :7159-7163
[5]   CLONING AND EXPRESSION OF A RAT-BRAIN ALPHA-2B-ADRENERGIC RECEPTOR [J].
FLORDELLIS, CS ;
HANDY, DE ;
BRESNAHAN, MR ;
ZANNIS, VI ;
GAVRAS, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (03) :1019-1023
[6]   ALPHA-1-ADRENOCEPTOR CLASSIFICATION - SHARPENING OCCAM RAZOR [J].
FORD, APDW ;
WILLIAMS, TJ ;
BLUE, DR ;
CLARKE, DE .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1994, 15 (06) :167-170
[7]  
FORRAY C, 1994, MOL PHARMACOL, V45, P703
[8]   ALPHA(1B)-RECEPTORS AND INTRACELLULAR CALCIUM MEDIATE SYMPATHETIC-NERVE INDUCED CONSTRICTION OF RAT IRIDEAL BLOOD-VESSELS [J].
GOULD, DJ ;
HILL, CE .
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1994, 50 (02) :139-150
[9]   GROSS TALK BETWEEN RECEPTORS MEDIATING CONTRACTION AND RELAXATION IN THE ARTERIOLES BUT NOT THE DILATOR MUSCLE OF THE RAT IRIS [J].
GOULD, DJ ;
VIDOVIC, M ;
HILL, CE .
BRITISH JOURNAL OF PHARMACOLOGY, 1995, 115 (05) :828-834
[10]   SYMPATHETIC TRANSMISSION TO THE DILATOR MUSCLE OF THE RAT IRIS [J].
HILL, CE ;
KLEMM, M ;
EDWARDS, FR ;
HIRST, GDS .
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1993, 45 (02) :107-123
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