CHILDHOOD MALIGNANT THYMOMA - CLINICAL, THERAPEUTIC, AND IMMUNOHISTOCHEMICAL CONSIDERATIONS

被引：14

作者：

KAPLINSKY, C ^{[1
]}

MOR, C ^{[1
]}

COHEN, IJ ^{[1
]}

GOSHEN, Y ^{[1
]}

YANIV, I ^{[1
]}

TAMARY, H ^{[1
]}

JABER, L ^{[1
]}

STARK, B ^{[1
]}

STERN, S ^{[1
]}

ZAIZOV, R ^{[1
]}

机构：

[1] TEL AVIV UNIV,SACKLER SCH MED,BEILINSON MED CTR,DEPT PATHOL,IL-49100 PETAH TIQWA,ISRAEL

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 1992年 / 9卷 / 03期

关键词：

IMMUNOCHEMISTRY; MALIGNANT THYMOMA; THERAPY;

D O I：

10.3109/08880019209016594

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Malignant thymomas are among the least common mediastinal tumors in the pediatric age group. Thymomas are considered malignant on the basis of macroscopic and microscopic invasiveness. As only 20 well-documented cases involving children have been reported in the literature, the pattern of responsiveness to therapy and the value of prognostic signs is obscure. Two cases of malignant pediatric thymomas are reported with pathognomonic histoimmunological features of aggressive thymoma. One was cured, with a follow-up of 70 months, and one died while on therapy. Analysis of the histological features and the immunoperoxidase staining displays the complexity of pediatric thymomas and the inability to prognosticate the outcome, respectively.

引用

页码：261 / 268

页数：8

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