REDUCED L-ARGININE LYSINE AND L-ARGININE ASPARTIC-ACID RATIOS IN AORTA FROM WATANABE HERITABLE HYPERLIPEMIC (WHHL) RABBIT

被引：6
作者：
CHINELLATO, A [1 ]
RAGAZZI, E [1 ]
DELAURETO, PP [1 ]
FASSINA, G [1 ]
机构：
[1] UNIV PADUA,DEPT ORGAN CHEM,I-35131 PADUA,ITALY
来源：
PHARMACOLOGICAL RESEARCH | 1992年 / 25卷 / 03期
关键词：
WHHL RABBIT; L-ARGININE; AORTA; HYPERLIPEMIA;
D O I：
10.1016/S1043-6618(05)80074-X
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
l-Arginine is the endogenous source of nitric oxide in the endothelial cells of blood vessels. In thoracic aorta from Watanabe heritable hyperlipidaemic (WHHL) rabbits, the l-arginine/lysine and l-arginine/aspartic acid ratios were reduced in comparison to New Zealand rabbit aorta. This result indicates that a variation in aortic arginine/lysine or arginine/aspartic acid ratios could be related to the hyperlipidaemic status. © 1992 The Italian Pharmacological Society.
引用
收藏
页码：255 / 258
页数：4
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