REDUCED L-ARGININE LYSINE AND L-ARGININE ASPARTIC-ACID RATIOS IN AORTA FROM WATANABE HERITABLE HYPERLIPEMIC (WHHL) RABBIT

被引：6

作者：

CHINELLATO, A ^{[1
]}

RAGAZZI, E ^{[1
]}

DELAURETO, PP ^{[1
]}

FASSINA, G ^{[1
]}

机构：

[1] UNIV PADUA,DEPT ORGAN CHEM,I-35131 PADUA,ITALY

来源：

PHARMACOLOGICAL RESEARCH | 1992年 / 25卷 / 03期

关键词：

WHHL RABBIT; L-ARGININE; AORTA; HYPERLIPEMIA;

D O I：

10.1016/S1043-6618(05)80074-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

l-Arginine is the endogenous source of nitric oxide in the endothelial cells of blood vessels. In thoracic aorta from Watanabe heritable hyperlipidaemic (WHHL) rabbits, the l-arginine/lysine and l-arginine/aspartic acid ratios were reduced in comparison to New Zealand rabbit aorta. This result indicates that a variation in aortic arginine/lysine or arginine/aspartic acid ratios could be related to the hyperlipidaemic status. © 1992 The Italian Pharmacological Society.

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收藏

页码：255 / 258

页数：4

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