RING-OPENING OF A FATTY EPOXIDE BY DIETHYLACETAMIDO MALONATE IN BASIC-MEDIUM BY PHASE-TRANSFER CATALYSIS OR UNDER MICROWAVE IRRADIATION

被引：12

作者：

ABENHAIM, D ^{[1
]}

LOUPY, A ^{[1
]}

MAHIEU, C ^{[1
]}

SEMERIA, D ^{[1
]}

机构：

[1] LOREAL SA,F-93601 AULNAY SOUS BOIS,FRANCE

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 13期

关键词：

D O I：

10.1080/00397919408010188

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A fatty epoxide (tetradecyl-oxirane) is reacted with diethyl acetamidomalonate in basic medium, with or without solvent under solid-liquid phase transfer catalysis with LiCl, or under microwave irradiation on supported reagents (KF/Al2O3/LiCl). The main product is a lactone which is formed after epoxide ring opening and subsequent cyclisation. We put here into evidence, for the first time, the conjugated advantages of ''dry media'' reactions, lithium salt effects and microwave irradiation.

引用

页码：1809 / 1816

页数：8

共 22 条

[1]

BERGER A, 1973, HELV CHIM ACTA, V56, P1838

[2] EASY MICHAEL ADDITION BY SOLID-LIQUID PHASE-TRANSFER CATALYSIS ABNORMAL REACTION OF N-ACETYLAMINOMALONATE [J].