RECENT DEVELOPMENTS IN IMMUNOTOXIN THERAPY

被引:41
|
作者
GHETIE, MA [1 ]
VITETTA, ES [1 ]
机构
[1] UNIV TEXAS,SW MED CTR,DEPT MICROBIOL,DALLAS,TX 75235
关键词
D O I
10.1016/0952-7915(94)90073-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Immunotoxin (IT) research has been ongoing for 15 years. During the past 2 years, work has focused on several areas: on improvements and developments in first- and second-generation ITs; the preparation of new immunotoxin constructs with anti-tumor activity; novel animal models for preclinical evaluation of immunotoxins; and clinical trials, which are now entering Phase II or III in humans.
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页码:707 / 714
页数:8
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