SOMATOSTATIN RECEPTORS IN HUMAN GASTROINTESTINAL CANCER

被引：0

作者：

DY, DY ^{[1
]}

MORRIS, DL ^{[1
]}

机构：

[1] UNIV NEW S WALES,ST GEORGE HOSP,DEPT SURG,KOGARAH,NSW 2217,AUSTRALIA

来源：

INTERNATIONAL JOURNAL OF ONCOLOGY | 1993年 / 3卷 / 03期

关键词：

AUTORADIOGRAPHY; GASTROINTESTINAL CANCER; RECEPTORS; XENOGRAFTS; SOMATOSTATIN;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Somatostatin receptors of human gastrointestinal cancer specimens and cell lines were measured using in vitro film autoradiography. Four colon and one gastric cancer cell lines when grown as xenografts were receptor-positive. Of the 31 human colorectal cancers, forty percent were receptor-positive, and there was an association between advanced stage and poorer differentiation with receptor status. Biopsy specimens of two gastric, one pancreatic and one esophageal cancers were negative for somatostatin receptors.

引用

页码：519 / 523

页数：5

共 36 条

[1]

BAKKER WH, 1990, J NUCL MED, V31, P1501

[2]

DREWINKO B, 1976, CANCER RES, V36, P467

[3] ANTIGENICITY OF NEWLY ESTABLISHED COLORECTAL-CARCINOMA CELL-LINES [J].

DURRANT, LG ;

ROBINS, RA ;

PIMM, MV ;

PERKINS, AC ;

ARMITAGE, NC ;

HARDCASTLE, JD ;

BALDWIN, RW .

BRITISH JOURNAL OF CANCER, 1986, 53 (01) :37-45

[4]

DY DY, 1992, CANCER RES, V52, P917

[5]

IFTIKHAR SY, 1988, EUR J SURG ONCOL, V18, P25

[6]

KRENNING EP, 1989, LANCET, V1, P242

[7]

Lamberts S W, 1987, Acta Endocrinol Suppl (Copenh), V286, P54

[8] SOMATOSTATIN-RECEPTOR IMAGING IN THE LOCALIZATION OF ENDOCRINE TUMORS [J].

LAMBERTS, SWJ ;

BAKKER, WH ;

REUBI, JC ;

KRENNING, EP .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (18) :1246-1249

[9] STUDIES ON THE MECHANISM OF ACTION OF THE INHIBITORY EFFECT OF THE SOMATOSTATIN ANALOG SMS-201-995 ON THE GROWTH OF THE PROLACTIN ADRENOCORTICOTROPIN-SECRETING PITUITARY TUMOR-7315A [J].

LAMBERTS, SWJ ;

REUBI, JC ;

UITERLINDEN, P ;

ZUIDERWIJK, J ;

VANDENWERFF, P ;

VANHAL, P .

ENDOCRINOLOGY, 1986, 118 (06) :2188-2194

[10] SOMATOSTATIN RECEPTORS [J].

LEWIN, MJM .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1986, 21 :42-46

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