HIGHLY REGIOSELECTIVE SYNTHESIS OF 1,7-DIPROTECTED 1,4,7,10-TETRAAZACYCLODODECANE DERIVATIVES

被引：35

作者：

ANELLI, PL

MURRU, M

UGGERI, F

VIRTUANI, M

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 18期

关键词：

D O I：

10.1039/c39910001317

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of dimethylformamide diethyl acetal with monoalkylated 1,4,7,10-tetraazacyclododecane derivatives 3, followed by hydrolysis of the tricyclic intermediates 4, selectivel affords 1,7-disubstituted tetraazamacrocycles 5.

引用

页码：1317 / 1318

页数：2

共 16 条

[1]

AIME S, IN PRESS INORG CHEM

[2] TRICYCLIC TRIS-AMINOMETHANES [J].

ATKINS, TJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (20) :6364-6365

[3]

ATKINS TJ, 1978, ORG SYNTH, V58, P86

[4]

ATKINS TJ, 1978, Patent No. 4085106

[5] NATURAL ABUNDANCE C-13-C-13 COUPLING OBSERVED VIA DOUBLE-QUANTUM COHERENCE [J].

BAX, A ;

FREEMAN, R ;

KEMPSELL, SP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (14) :4849-4851

[6] COMPLEXES OF POLYAZA MACROCYCLES BEARING PENDENT COORDINATING GROUPS [J].

BERNHARDT, PV ;

LAWRANCE, GA .

COORDINATION CHEMISTRY REVIEWS, 1990, 104 (02) :297-343

[7]

DESHPANDE SV, 1990, J NUCL MED, V31, P473

[8] TRANSFER OF HYDROGEN FROM ORTHOAMIDES - SYNTHESIS, STRUCTURE, AND REACTIONS OF HEXAHYDRO-6BH-2A,4A,6A-TRIAZACYCLOPENTA[CD]PENTALENE AND PERHYDRO-3A,6A,9A-TRIAZAPHENALENE [J].

ERHARDT, JM ;

GROVER, ER ;

WUEST, JD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (20) :6365-6369

[9]

KADEN TA, 1984, TOP CURR CHEM, V121, P154

[10] A ROUTE TO THE PYRROLIZIDINE RING-SYSTEM USING A NOVEL RADICAL CYCLIZATION [J].

LATHBURY, DC ;

PARSONS, PJ ;

PINTO, I .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1988, (02) :81-82

← 1 2 →