SERUM ERYTHROPOIETIN QUANTITATION IN PREGNANCY USING AN ENZYME-LINKED IMMUNOASSAY

被引：14

作者：

HARSTAD, TW ^{[1
]}

MASON, RA ^{[1
]}

COX, SM ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,DALLAS,TX 75230

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 1992年 / 9卷 / 04期

关键词：

D O I：

10.1055/s-2007-994778

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

During normal pregnancy there is a decrease in the hematocrit due to a disproportionate increase in the blood volume compared with the red cell mass. Using a new enzyme-linked immunoassay (Amgen Diagnostics), serum erythropoietin was quantified in normal nonanemic pregnancies throughout gestation and in third trimester anemic patients. We found that the mean hematocrit in normal pregnancy reached a nadir late in the second trimester and the serum erythropoietin plateaued at a 50% increase. Those pregnancies complicated by anemia defined by a hematocrit less than 30 vol% demonstrated a statistically significant increase in serum erythropoietin above those not anemic.

引用

页码：233 / 235

页数：3

共 4 条

[1]

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[2]

Howells M.R., Jones S.E., Napier J.A.F., Sanders K., Cavill I., Erythropoiesis in pregnancy, Br J Haematol, 64, pp. 595-596, (1986)

[3]

Eichner E.R., Spivak J.L., Sims P.J., Selby G.B., The anemias in hematology-1989, Education Program American Society of Hematology, pp. 1-8, (1989)

[4]

Product information and manual—1989 (1900 Terrace Lane

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