ABSENCE OF GASTRIC UREASE IN GERM-FREE ANIMALS

被引：50

作者：

DELLUVA, AM

MARKLEY, K

DAVIES, RE

机构：

[1] Department of Biochemistry, School of Medicine University of Pennsylvania, Philadelphia, PA

[2] National Institutes of Arthritis, Metabolic Diseases National Institutes of Health, Bethesda, MD

[3] Laboratories of Biochemistry, Department of Animal Biology School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1968年 / 151卷 / 03期

关键词：

D O I：

10.1016/0005-2744(68)90011-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1.Measurements were made of the urease (urea amidohydrolase, EC 3.5.1.5) content of the gastric mucosae of conventional, germ free, and fetal animals to test whether gastric urease arises from micro-organisms or is constitutive. 2. 2.Homogenates of gastric mucosae of conventional sheep, dogs, cats, rats, guinea pigs, and chickens; of germ-free rats, guinea pigs, chickens, dogs, cats, and pigs; and of fetal dogs, cats, rats, sheep, and humans were prepared and analyzed for urease activity. 3. 3.There was no urease in the gastric mucosae of the germ-free or fetal animals, although enzymic activity was usually found in the same tissue from their conventional adult counterparts, which had a wide range of enzymatic activity. © 1968.

引用

页码：646 / &

共 20 条

[1]

BELDING ME, 1963, J LAB CLIN MED, V61, P560

[2]

CARDIN A., 1933, ARCH SCI BIOL, V19, P76

[3]

CONWAY EJ, 1959, GASTROENTEROLOGY, V37, P449

[4] AMMONIA IN THE GUT [J].