LYMPHOCYTE BETA-2-ADRENOCEPTORS AND PLASMA-CATECHOLAMINES IN FETAL HYPOXIA

被引：7

作者：

SANTALA, M

SAARIKOSKI, S

CASTREN, O

PARVIAINEN, M

机构：

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 1990年 / 30卷 / 03期

关键词：

catecholamines; delivery; hypoxia; lymphocytes; receptors; β-adrenergic;

D O I：

10.1159/000293246

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Conclusive evidence has been furnished that the β2-adrenoceptor density in circulating lymphocytes is related to that of β2-adrenoceptors in tissues from the same subjects. This study was designed to evaluate the effect of fetal hypoxia on lymphocyte β2-adrenoceptor density. The material consisted of 8 hypoxic newborns, 4 delivered by vacuum extraction and 4 by Caesarean section, after approximately 10 h parturition. The control group consisted of 8 vaginally delivered newborns without hypoxia. Umbilical plasma adrenaline and noradrenaline were significantly elevated in the hypoxic newborns. Their lymphocyte β2-adrenoceptor density was lower (p<0.01) than that in the controls. A plausible explanation for this finding might be downregulation of β2-adrenoceptors because of elevated plasma catecholamine level.

引用

页码：150 / 154

页数：5

共 35 条

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