THE ROSTRAL AND CAUDAL VENTROLATERAL MEDULLA IN YOUNG SPONTANEOUSLY HYPERTENSIVE RATS

被引：26
|
作者：
SMITH, JK
BARRON, KW
机构：
[1] UNIV KENTUCKY,COLL MED,TOBACCO & HLTH RES INST,DEPT PHYSIOL & BIOPHYS,COOPER & UNIV DR,LEXINGTON,KY 40546
[2] UNIV ALABAMA,SCH MED,DEPT INTERNAL MED,BIRMINGHAM,AL 35233
来源：
BRAIN RESEARCH | 1990年 / 506卷 / 01期
关键词：
Cardiovascular effect; Heart rate; Hypertension; l-Glutamate; Mean arterial pressure; Spontaneously hypertensive rat; Tetrodotoxin; Ventrolateral medulla; Wistar-Kyoto rat;
D O I：
10.1016/0006-8993(90)91213-Z
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
This study was designed to compare the cardiovascular influences of the rostral ventrolateral medulla (RVLM) and the caudal ventrolateral medulla (CVLM) in young (5-6 weeks) spontaneously hypertensive (SH) and normotensive Wistar-Kyoto (WKY) rats. SH and WKY groups had similar pressor and depressor responses to microinjection of l-glutamate into the RVLM and the CVLM, respectively. In addition the results of this study indicate a reduced tonic sympathoinhibitory function of the CVLM in young SH rats, which may contribute to the development of hypertension in the spontaneously hypertensive rat. © 1990.
引用
收藏
页码：153 / 158
页数：6
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