INVITRO METABOLISM OF ETOPOSIDE (VP-16-213) BY LIVER-MICROSOMES AND IRREVERSIBLE BINDING OF REACTIVE INTERMEDIATES TO MICROSOMAL PROTEINS

被引：80
作者：
HAIM, N
NEMEC, J
ROMAN, J
SINHA, BK
机构：
[1] NCI,CLIN ONCOL BRANCH,BLDG 10,RM 6N-119,BETHESDA,MD 20892
[2] UNIFORMED SERV UNIV HLTH SCI,DIV CLIN PHARMACOL,BETHESDA,MD 20814
[3] NCI,FREDERICK CANC RES FACIL,CHEM SYNTH & ANAL LABS,FREDERICK,MD 21701
来源：
BIOCHEMICAL PHARMACOLOGY | 1987年 / 36卷 / 04期
关键词：
D O I：
10.1016/0006-2952(87)90362-5
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：527 / 536
页数：10
相关论文
共 35 条
[1]  
AMES MM, 1983, CANCER RES, V43, P500
[2]  
BACHUR NR, 1978, CANCER RES, V38, P1745
[3]  
BEND JR, 1972, J PHARMACOL EXP THER, V183, P206
[4]  
COLOMBO T, 1982, CANCER CHEMOTH PHARM, V7, P127
[5]  
CREAVEN PJ, 1982, CANCER CHEMOTH PHARM, V7, P133
[6]  
DINCALCI M, 1986, CANCER RES, V46, P2566
[7]  
DOW LW, 1983, CANCER RES, V43, P5699
[8]  
EVANS WE, 1982, CANCER CHEMOTH PHARM, V7, P147
[9]   INHIBITION OF HEPATIC OXIDATIVE XENOBIOTIC METABOLISM BY PIPERONYL BUTOXIDE [J].
FRANKLIN, MR .
BIOCHEMICAL PHARMACOLOGY, 1972, 21 (24) :3287-+
[10]  
GRAM TE, 1974, DRUG METAB DISPOS, V2, P254
1234