Carbapenem resistance: overview of the problem and future perspectives

被引：447
作者：
Meletis, Georgios [1 ]
机构：
[1] Labnet Labs, Agiou Dimitriou Str 161, Thessaloniki 53337, Greece
来源：
THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE | 2016年 / 3卷 / 01期
关键词：
antibiotic resistance; carbapenemases; carbapenems;
D O I：
10.1177/2049936115621709
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-health problem of global dimensions. This type of antimicrobial resistance, especially when mediated by transferable carbapenemase-encoding genes, is spreading rapidly causing serious outbreaks and dramatically limiting treatment options. In this article, important key points related to carbapenem resistance are reviewed and future perspectives are discussed.
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页码：15 / 21
页数：7
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