INHIBITION OF MIXED-FUNCTION OXIDATIONS BY SUBSTRATES FORMING REDUCED CYTOCHROME-P-450 METABOLIC-INTERMEDIATE COMPLEXES

被引：171
作者：
FRANKLIN, MR
机构：
[1] UNIV UTAH, COLL PHARM, DEPT BIOPHARMACEUT SCI, SALT LAKE CITY, UT 84112 USA
[2] UNIV UTAH, COLL MED, DEPT PHARMACOL, SALT LAKE CITY, UT 84112 USA
来源：
PHARMACOLOGY & THERAPEUTICS PART A-CHEMOTHERAPY TOXICOLOGY AND METABOLIC INHIBITORS | 1977年 / 2卷 / 01期
关键词：
D O I：
10.1016/0362-5478(77)90015-8
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：227 / 245
页数：19
相关论文
共 60 条
[1]   POLYCHLORINATED BIPHENYLS - NEW TYPE OF INDUCER OF CYTOCHROME P-448 IN LIVER - (CYTOCHROME P-450 RATS ARYL HYDROCARBON HYDROXYLASE-ENZYME INDUCTION MICROSOMAL ENZYMES) [J].
ALVARES, AP ;
BICKERS, DR ;
KAPPAS, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (05) :1321-1325
[2]   INHIBITION OF MICROSOMAL DRUG METABOLISM BY METHYLENEDIOXYBENZENES [J].
ANDERS, MW .
BIOCHEMICAL PHARMACOLOGY, 1968, 17 (11) :2367-&
[3]  
BUENING MK, 1976, DRUG METAB DISPOS, V4, P244
[4]  
BUENING MK, 1976, DRUG METAB DISPOS, V4, P556
[5]  
BUENING MK, 1974, DRUG METAB DISPOS, V2, P386
[6]   PHOTOCHEMICAL ACTION SPECTRUM OF TERMINAL OXIDASE OF MIXED FUNCTION OXIDASE SYSTEMS [J].
COOPER, DY ;
LEVIN, S ;
NARASIMHULU, S ;
ROSENTHAL, O ;
ESTABROOK, RW .
SCIENCE, 1965, 147 (3656) :400-+
[7]  
COX PJ, 1972, BIOCHEM J, V130, pP87
[8]  
ELCOMBE CR, 1976, H-S Z PHYSIOL CHEM, V357, P1026
[9]   CUMENE HYDROPEROXIDE-MEDIATED FORMATION OF INHIBITED COMPLEXES OF METHYLENEDIOXYPHENYL COMPOUNDS WITH CYTOCHROME-P-450 [J].
ELCOMBE, CR ;
BRIDGES, J ;
NIMMOSMITH, RH ;
WERRINGLOER, J .
BIOCHEMICAL SOCIETY TRANSACTIONS, 1975, 3 (06) :967-970
[10]   STUDIES ON INTERACTION OF SAFROLE WITH RAT HEPATIC MICROSOMES [J].
ELCOMBE, CR ;
BRIDGES, JW ;
GRAY, TJB ;
NIMMOSMITH, RH ;
NETTER, KJ .
BIOCHEMICAL PHARMACOLOGY, 1975, 24 (15) :1427-1433
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