EXCITATORY ADRENERGIC RECEPTORS IN HUMAN STOMACH AND PYLORUS

被引:20
作者
HAFFNER, JFW
LIAVAG, I
SETEKLEIV, J
机构
[1] Institute of Pharmacology, University of Oslo, Blindem
[2] Surgical Department II, Ullevål Hospital
[3] Institute of Pharmacology, University of Oslo, Blindern
关键词
Adrenergic blocking agents; Adrenergic receptors; Epinephrine; Norepinephrine; Pylorus; Smooth muscle; Stomach;
D O I
10.3109/00365526909179922
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The responses to cholinergic and adrenergic drugs in human muscle strips from stomach and pylorus have been studied in vitro. Acetylcholine and carbacholine induced contractions in all preparations tested. The responses were blocked by atropine. The response to adrenaline and noradrenaline elicited contractions in some preparations; in others biphasic responses or inhibition was obtained. Reversal of the response was also produced in some preparations by increasing the dose. The studies indicate excitatory adrenergic αreceptors in addition to inhibitory α and βreceptors. © 1969 Informa UK Ltd.
引用
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页码:145 / +
页数:1
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