NEW QUINOLINE DERIVATIVES - SYNTHESIS AND EVALUATION FOR ANTIINFLAMMATORY AND ANALGESIC PROPERTIES .2.

被引：0
|
作者：
SAVINI, L
MASSARELLI, P
PELLERANO, C
BRUNI, G
机构：
[1] UNIV BANCHI,DIPARTIMENTO FARM CHIM TECNOL,SOTTO 55,I-53100 SIENA,ITALY
[2] UNIV SCOTTE,IST FARMACOL,I-53100 SIENA,ITALY
来源：
FARMACO | 1993年 / 48卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The synthesis of new halogenated series of 4-anilinoquinoline-3-carboxylic acids, N-[3-carboxyquinolyl(4)]anthranilic acids and their corresponding esters is reported. These have been obtained by reacting 4-chloro-3-carbethoxy-quinolines with variously substituted anilines and methyl anthranilate respectively. The synthesized compounds were tested for antiinflammatory and analgesic activities; some of them showed a good analgesic activity, sometimes higher than that of indomethacin, used as reference drug.
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页码：805 / 825
页数：21
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