RETINAL MANIFESTATIONS OF NEUROFIBROMATOSIS - DIAGNOSIS AND MANAGEMENT

被引：55

作者：

DESTRO, M ^{[1
]}

DAMICO, DJ ^{[1
]}

GRAGOUDAS, ES ^{[1
]}

BROCKHURST, RJ ^{[1
]}

PINNOLIS, MK ^{[1
]}

ALBERT, DM ^{[1
]}

TOPPING, TM ^{[1
]}

PULIAFITO, CA ^{[1
]}

机构：

[1] HARVARD UNIV, MASSACHUSETTS EYE & EAR INFIRM, SCH MED, DEPT OPHTHALMOL, BOSTON, MA 02114 USA

来源：

ARCHIVES OF OPHTHALMOLOGY | 1991年 / 109卷 / 05期

关键词：

D O I：

10.1001/archopht.1991.01080050076033

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Five patients presented with vision-threatening retinal tumors and systemic signs of neurofibromatosis, including neurofibromatosis type 1 (four patients) and familial cafe-au-lait spots (one patient). These tumors included large retinal astrocytic hamartomas, multiple retinal capillary hemangiomas, and combined hamartomas of the retina and retinal pigment epithelium, which resulted in rubeotic glaucoma, vitreous hemorrhage, and retinal detachment. Surgical therapy included retinal cryopexy, xenon and argon photocoagulation, scleral buckling, and pars plana vitrectomy with excisional retinal biopsy. Retinal tumors may result in marked visual loss in patients with neurofibromatosis, and vitreoretinal surgery may restore useful vision in some of these patients.

引用

页码：662 / 666

页数：5

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