CHEMISTRY OF TOXIC RANGE PLANTS - DETERMINATION OF PYRROLIZIDINE ALKALOID CONTENT AND COMPOSITION IN SENECIO SPECIES BY NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY

被引：85

作者：

MOLYNEUX, RJ ^{[1
]}

JOHNSON, AE ^{[1
]}

ROITMAN, JN ^{[1
]}

BENSON, ME ^{[1
]}

机构：

[1] USDA,ARS,POISONOUS PLANT RES LAB,LOGAN,UT 84321

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1979年 / 27卷 / 03期

关键词：

D O I：

10.1021/jf60223a002

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

The pyrrolizidine alkaloid and corresponding N-oxide contents of small samples ofSenecio longilobus, S. riddellii, S. jacobaea, and S. vulgaris have been measured using nuclear magnetic resonance spectroscopy. The percentages of the individual alkaloids seneciphylline, senecionine, riddelliine, and retrorsine in the total alkaloid mixture have also been determined from the same NMR spectra. Exceptionally high total alkaloid contents were found for S. longilobus and S. riddellii relative to most Senecio sp. The technique provides a rapid, facile method for examination of plant samples in order to evaluate the hepatotoxicity hazard to animals and humans and for regulation of dose rate of pyrrolizidine alkaloids in animal feeding experiments. © 1979, American Chemical Society. All rights reserved.

引用

页码：494 / 499

页数：6

共 20 条

[1] SENECIO ALKALOIDS - THE COMPOSITION OF HIERACIFOLINE AND JACOBINE [J].