Chromosomal Translocation t (10;19) (q11.2;q13.4) in an Infertile Male

被引：10

作者：

Kara, Murat ^{[1
]}

Sen, Askin ^{[2
]}

Cetin, Esin Sakalli ^{[3
,4
]}

Kargun, Kursat ^{[5
]}

机构：

[1] Mugla Sitki Kocman Univ, Fac Med, Dept Med Genet, Mugla, Turkey

[2] Firat Univ Hosp, Fac Med, Dept Med Genet, Elazig, Turkey

[3] Mugla Sitki Kocman Univ, Fac Med, Dept Med Biol, Mugla, Turkey

[4] Mugla Sitki Kocman Univ, Fac Med, Dept Med Biol, Mugla, Turkey

[5] Firat Univ Hosp, Dept Med Genet Lab, Elazig, Turkey

来源：

EURASIAN JOURNAL OF MEDICINE | 2014年 / 46卷 / 03期

关键词：

Chromosomal translocation; infertility;

D O I：

10.5152/eajm.2014.33

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chromosomal rearrangements are usually associated with male factor infertility. We report here a 34-year-old man suffering from primary infertility for 15 years. The cytogenetic analysis and investigation of Y-chromosome microdeletions were performed. A reciprocal balanced translocation t (10; 19) (q11.2;q13.4) was found in oligozoo-spermic infertile men with no Y-chromosome microdeletions. In this case, we aimed to evaluate the 46,XY, t (10;19) (q11.2;q13.4) karyotype, which was detected through a cytogenetic analysis of a person referred to our genetic laboratory due to primary infertility, in the light of the literature.

引用

页码：220 / 223

页数：4

共 17 条

[11]

Poongothai J, 2009, SINGAP MED J, V50, P336

[12] Cytogenetics of infertile men [J].

VanAssche, E ;

Bonduelle, M ;

Tournaye, H ;

Joris, H ;

Verheyen, G ;

Devroey, P ;

VanSteirteghem, A ;

Liebaers, I .

HUMAN REPRODUCTION, 1996, 11 :1-24

[13] De novo chromosomal translocation t(3;5)(q13;q35) in an infertile man [J].

Venkateshwari, A. ;

Srilekha, A. ;

Begum, A. ;

Sujatha, M. ;

Sunitha, T. ;

Nallari, P. ;

Jyothy, A. .

ANDROLOGIA, 2011, 43 (06) :428-430

[14] Sperm fluorescence in situ hybridization study of meiotic segregation and an interchromosomal effect in carriers of t(11;18) [J].

Vozdova, Miluse ;

Oracova, Eva ;

Horinova, Vera ;

Rubes, Jiri .

HUMAN REPRODUCTION, 2008, 23 (03) :581-588

[15] The Genetics of Male Infertility [J].

Walsh, Thomas J. ;

Pera, Renee Reijo ;

Turek, Paul J. .

SEMINARS IN REPRODUCTIVE MEDICINE, 2009, 27 (02) :124-136

[16]

Wiland E, 2002, MED SCI MONITOR, V8, pCR394

[17] Meiotic segregation analysis of reciprocal translocations, both in sperms and blastomeres [J].

Yakut, T ;

Ercelen, N ;

Acar, H ;

Kimya, Y ;

Egeli, U .

AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2006, 140A (10) :1074-1082

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