Chromosomal Translocation t (10;19) (q11.2;q13.4) in an Infertile Male

被引：10

作者：

Kara, Murat ^{[1
]}

Sen, Askin ^{[2
]}

Cetin, Esin Sakalli ^{[3
,4
]}

Kargun, Kursat ^{[5
]}

机构：

[1] Mugla Sitki Kocman Univ, Fac Med, Dept Med Genet, Mugla, Turkey

[2] Firat Univ Hosp, Fac Med, Dept Med Genet, Elazig, Turkey

[3] Mugla Sitki Kocman Univ, Fac Med, Dept Med Biol, Mugla, Turkey

[4] Mugla Sitki Kocman Univ, Fac Med, Dept Med Biol, Mugla, Turkey

[5] Firat Univ Hosp, Dept Med Genet Lab, Elazig, Turkey

来源：

EURASIAN JOURNAL OF MEDICINE | 2014年 / 46卷 / 03期

关键词：

Chromosomal translocation; infertility;

D O I：

10.5152/eajm.2014.33

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chromosomal rearrangements are usually associated with male factor infertility. We report here a 34-year-old man suffering from primary infertility for 15 years. The cytogenetic analysis and investigation of Y-chromosome microdeletions were performed. A reciprocal balanced translocation t (10; 19) (q11.2;q13.4) was found in oligozoo-spermic infertile men with no Y-chromosome microdeletions. In this case, we aimed to evaluate the 46,XY, t (10;19) (q11.2;q13.4) karyotype, which was detected through a cytogenetic analysis of a person referred to our genetic laboratory due to primary infertility, in the light of the literature.

引用

页码：220 / 223

页数：4

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