AN ANIMAL-MODEL OF KAPOSIS-SARCOMA .2. PATHOGENESIS OF DIMETHYL HYDRAZINE INDUCED ANGIOSARCOMA AND COLORECTAL-CANCER IN 3 MOUSE STRAINS

被引：0

作者：

MADARNAS, P

DUBE, M

ROLAPLESZCZYNSKI, M

NIGAM, VN

机构：

[1] UNIV SHERBROOKE,FAC MED,DEPT ANAT & BIOL CELLULAIRE,SHERBROOKE J1K 2R1,QUEBEC,CANADA

[2] UNIV SHERBROOKE,FAC MED,DEPT PEDIAT,SHERBROOKE J1K 2R1,QUEBEC,CANADA

来源：

ANTICANCER RESEARCH | 1992年 / 12卷 / 01期

关键词：

DIMETHYLHYDRAZINE; ANGIOSARCOMA; KAPOSIS SARCOMA; COLORECTAL CANCER;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

CDI, C57B1/6 and DBA2 mice were subjected to dimethyl hydrazine (DMH) carcinogenesis to determine incidences of various types of tumors developing internally in the three strains. The animals were also screened for skin angiosarcomas. Skin lesions histologically similar to cutaneous AIDS associated Kaposi's sarcoma were observed in CD1 mice. Angiosarcomas predominated over colorectal tumors in C57Bl/6 and DBA2 mice, whereas the reverse was true for CD1 mice. The visceral angiosarcomas had both histological similarities and differences with visceral AIDS associated Kaposi's sarcoma.

引用

页码：113 / 117

页数：5