A Clidinium Potentiometric Membrane Sensor for Determination of Clidinium in Pharmaceutical Formulation

被引:0
作者
Karimi, Anahita [1 ]
Faridbod, Farnoush [1 ,2 ]
Safaraliee, Leila [1 ]
机构
[1] Univ Tehran, Ctr Excellence Electrochem, Tehran, Iran
[2] Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Tehran, Iran
来源
ANALYTICAL & BIOANALYTICAL ELECTROCHEMISTRY | 2011年 / 3卷 / 05期
关键词
Clidinium Bromide; Potentiometric Sensor; PVC membrane; Ion-Pair;
D O I
暂无
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
This work introduces a PVC membrane sensor for determination of clidinium active ingredient. For the membrane preparation, clidinium-tetraphenyl borate ion-pair was employed as a sensing material in the PVC membrane. Several plasticizers were studied in the membrane composition dibutyl phthalate (DBP), benzylacetat (BA), and nitrobenzene (NB). After a series of experiments, the best electrode response was obtained from a membrane composed of NB. The electrodes illustrated a fast, stable and Nernstian response over a wide clidinium bromide concentration range of 1x10(-5) to 1x10(-1) M, in the pH range of 4.0-10.0.
引用
收藏
页码:532 / 542
页数:11
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