A SINGLE FRAGMENT OF A MALARIA MEROZOITE SURFACE PROTEIN REMAINS ON THE PARASITE DURING RED-CELL INVASION AND IS THE TARGET OF INVASION-INHIBITING ANTIBODIES

被引：502

作者：

BLACKMAN, MJ

HEIDRICH, HG

DONACHIE, S

MCBRIDE, JS

HOLDER, AA

机构：

[1] NATL INST MED RES,DIV PARASITOL,THE RIDGEWAY,MILL HILL,LONDON NW7 1AA,ENGLAND

[2] MAX PLANCK INST BIOCHEM,W-8033 MARTINSRIED,GERMANY

[3] UNIV EDINBURGH,DEPT ZOOL,EDINBURGH EH9 3JT,MIDLOTHIAN,SCOTLAND

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 1990年 / 172卷 / 01期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1084/jem.172.1.379

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A complex of polypeptides derived from a precursor is present on the surface of the malaria merozoite. During erythrocyte invasion only a small fragment from this complex is retained on the parasite surface and carried into the newly infected red cell. Antibodies to this fragment will interrupt invasion. © 1990, Rockefeller University Press., All rights reserved.

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收藏

页码：379 / 382

页数：4

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