REGIOSELECTIVE ENZYMATIC DEACETYLATION OF SUCROSE OCTAACETATE IN ORGANIC-SOLVENTS

被引：20

作者：

PALMER, DC ^{[1
]}

TERRADAS, F ^{[1
]}

机构：

[1] MCNEIL SPECIALTY PROD CO, ATHENS, GA 30608 USA

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 11期

关键词：

D O I：

10.1016/0040-4039(94)88316-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first examples of deacetylation of sucrose octaacetate using proteases and lipases in organic solvents are reported. The regiochemistry of the product sucrose hepta-, hexa- and pentaacetates was established by perdeuteroacetylation and H-1-NMR. Preparation of key intermediates in the commercial synthesis of the high intensity sweetener, sucralose was achieved.

引用

页码：1673 / 1676

页数：4

共 47 条

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