SPOREAMICIN-A, A NEW MACROLIDE ANTIBIOTIC .1. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

被引：12

作者：

YAGINUMA, S

MORISHITA, A

ISHIZAWA, K

MUROFUSHI, S

HAYASHI, M

MUTOH, N

机构：

[1] Research Labolatories, Toyo Jozo Co., Ltd., Ohito

来源：

JOURNAL OF ANTIBIOTICS | 1992年 / 45卷 / 05期

关键词：

D O I：

10.7164/antibiotics.45.599

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Sporeamicin A, a novel antibiotic, was isolated from the culture filtrate of an actinomycete. The producing organism, strain L53-18, was taxonomically assigned as a species of the genus Saccaropolyspora. The antibiotic was extracted with chloroform and was then purified by crystallization. It was obtained as colorless prisms from ethanolic solutions. Sporeamicin A exhibited a strong UV absorption peak at 276 nm. The molecular formula of sporeamicin A was determined to be C37H63NO12.

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页码：599 / 606

页数：8

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