TOBACCO-SPECIFIC N-NITROSAMINES IN TOBACCO AND MAINSTREAM SMOKE OF INDIAN CIGARETTES

被引:4
|
作者
KUMAR, R
SIDDIQI, M
TRICKER, AR
PREUSSMANN, R
机构
[1] GERMAN CANC RES CTR,INST TOXICOL & CHEMOTHERAPY,NEUENHEIMER FELD 280,W-6900 HEIDELBERG,GERMANY
[2] UNIV KASHMIR,DEPT PHARMACEUT SCI,SRINAGAR 190006,JAMMU & KASHMIR,INDIA
[3] UNIV KASHMIR,DEPT BIOCHEM,SRINAGAR 190006,JAMMU & KASHMIR,INDIA
关键词
D O I
10.1016/0278-6915(91)90081-H
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Different brands of Indian cigarettes were analysed, by gas chromatography-thermal energy analysis, for the presence of carcinogenic tobacco-specific N-nitrosamines (TSNA) in both tobacco and mainstream smoke. Preformed TSNA in cigarette tobacco ranged between 68 and 730 ng N-nitrosonornicotine (NNN)/cigarette, between 19 and 174 ng 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)/cigarette and between 98 and 519 ng N-nitrosoanabasine (NAB) together with N-nitroso-anatabine (NAT)/cigarette. The amounts of NNN, NNK and NAB/NAT in mainstream smoke were 11-156, 7-73 and 17-146 ng/cigarette, respectively.
引用
收藏
页码:405 / 407
页数:3
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