Data for the measurement of serum vitamin D metabolites in childhood acute lymphoblastic leukemia survivors

被引:3
作者
Delvin, E. [1 ,2 ]
Boisvert, M. [1 ]
Lecours, M. -A. [1 ]
Theoret, Y. [1 ,3 ,4 ]
Kaufmann, M. [5 ]
Jones, G. [5 ]
Levy, E. [1 ,6 ]
机构
[1] Univ Montreal, CHU Ste Justine Res Ctr, Montreal, PQ, Canada
[2] Univ Montreal, Dept Biochem, Montreal, PQ, Canada
[3] Univ Montreal, CHU Ste Justine, Dept Clin Biochem, Clin Pharmacol Unit, Montreal, PQ, Canada
[4] Univ Montreal, Dept Pharmacol, Montreal, PQ, Canada
[5] Queens Univ, Dept Biomed & Mol Sci, Kingston, ON, Canada
[6] Univ Montreal, Dept Nutr, Montreal, PQ, Canada
关键词
D O I
10.1016/j.dib.2018.04.030
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This article describes data related to a companion research paper entitled "Vitamin D nutritional status and bone turnover biomarkers in childhood acute lymphoblastic leukemia (CALL) survivors." (Delvin et al., submitted for publication) [1]. Various methods for the measurement of serum 250HD(3), the accepted biomarker for assessing vitamin D nutritional status, have been described (Le Goff et al., 2015; Jensen et al., 2016) [2,3]. This article describes a novel mass spectrometry-QTOF method for the quantification of circulating 250HD(3), 3-epi-250HD(3) and 24,25(OH)(2)D-3. It provides the description of the extraction, chromatography and mass spectrometry protocols, a sample of mass spectra obtained from standards and extracted serum, and a comparison with another HPLC-MS/MS (Jensen et al., 2016) [3] method for the measurement of serum concentrations of 250HD(3). (C) 2018 The Authors. Published by Elsevier Inc.
引用
收藏
页码:1427 / 1432
页数:6
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