PHARMACOKINETICS OF ERYTHROMYCIN IN PATIENTS WITH SEVERE CIRRHOSIS - RESPECTIVE INFLUENCE OF DECREASED SERUM BINDING AND IMPAIRED LIVER METABOLIC CAPACITY

被引：54
作者：
BARRE, J
MALLAT, A
ROSENBAUM, J
DEFORGES, L
HOUIN, G
DHUMEAUX, D
TILLEMENT, JP
机构：
[1] HOP HENRI MONDOR, DEPT PHARMACOL CLIN, F-94010 CRETEIL, FRANCE
[2] HOP HENRI MONDOR, SERV BACTERIOL, F-94010 CRETEIL, FRANCE
[3] HOP HENRI MONDOR, SERV HEPATOL & GASTROENTEROL, F-94010 CRETEIL, FRANCE
[4] HOP HENRI MONDOR, INSERM, U99, F-94010 CRETEIL, FRANCE
[5] UNIV TOULOUSE 3, FAC PHARM, PHARMACOL LAB, F-31400 TOULOUSE, FRANCE
来源：
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1987年 / 23卷 / 06期
关键词：
D O I：
10.1111/j.1365-2125.1987.tb03111.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：753 / 757
页数：5
相关论文
共 13 条
[1]   INTERSUBJECT AND DOSE-RELATED VARIABILITY AFTER INTRAVENOUS ADMINISTRATION OF ERYTHROMYCIN [J].
AUSTIN, KL ;
MATHER, LE ;
PHILPOT, CR ;
MCDONALD, PJ .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 10 (03) :273-279
[2]   DECREASED ALPHA-1-ACID GLYCOPROTEIN IN LIVER-CIRRHOSIS - CONSEQUENCES FOR DRUG PROTEIN-BINDING [J].
BARRE, J ;
HOUIN, G ;
ROSENBAUM, J ;
ZINI, R ;
DHUMEAUX, D ;
TILLEMENT, JP .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 18 (04) :652-653
[3]  
CHABBERT Y, 1957, REV FR ETUD CLIN BIO, V2, P636
[4]   BILIARY-EXCRETION OF ERYTHROMYCIN AFTER PARENTERAL ADMINISTRATION [J].
CHELVAN, P ;
HAMILTONMILLER, JMT ;
BRUMFITT, W .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 8 (03) :233-235
[5]  
GREENBLATT DJ, 1982, NEW ENGL J MED, V306, P1081
[6]   PHARMACOKINETICS OF ERYTHROMYCIN IN NORMAL AND ALCOHOLIC LIVER-DISEASE SUBJECTS [J].
HALL, KW ;
NIGHTINGALE, CH ;
GIBALDI, M ;
NELSON, E ;
BATES, TR ;
DISANTO, AR .
JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 22 (07) :321-325
[7]   PHARMACOKINETICS OF SINGLE-DOSE ERYTHROMYCIN IN NORMAL AND ALCOHOLIC LIVER-DISEASE SUBJECTS [J].
KROBOTH, PD ;
BROWN, A ;
LYON, JA ;
KROBOTH, FJ ;
JUHL, RP .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1982, 21 (01) :135-140
[8]  
PRANDOTA J, 1980, J INT MED RES, V8, P1
[9]   TRANSECTION OF ESOPHAGUS FOR BLEEDING ESOPHAGEAL VARICES [J].
PUGH, RNH ;
MURRAYLY.IM ;
DAWSON, JL ;
PIETRONI, MC ;
WILLIAMS, R .
BRITISH JOURNAL OF SURGERY, 1973, 60 (08) :646-649
[10]  
Rowland M, 1980, CLIN PHARMACOKINETIC
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