FOCI OF INCREASED T2 SIGNAL INTENSITY IN MR IMAGES OF HEALTHY ELDERLY SUBJECTS - A FOLLOW-UP-STUDY

被引：42

作者：

AUSTROM, MG

THOMPSON, RF

HENDRIE, HC

NORTON, J

FARLOW, MR

EDWARDS, MK

DEAN, R

机构：

[1] INDIANA UNIV,SCH MED,DEPT PSYCHIAT,534 CLIN DR,CG 110,INDIANAPOLIS,IN 46202

[2] INDIANA UNIV,SCH MED,DEPT MED GENET,INDIANAPOLIS,IN 46202

[3] INDIANA UNIV,SCH MED,DEPT NEUROL,INDIANAPOLIS,IN 46202

[4] INDIANA UNIV,SCH MED,DEPT RADIOL,INDIANAPOLIS,IN 46202

[5] BALL STATE UNIV,DEPT PSYCHOL,MUNCIE,IN 47306

来源：

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY | 1990年 / 38卷 / 10期

关键词：

D O I：

10.1111/j.1532-5415.1990.tb01377.x

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

An 18‐month follow‐up study was conducted on 26 healthy elderly subjects with and without foci of increased T2 signal intensity on MR imaging. The subjects did not differ with respect to health status or cognitive performance as measured by the Cognitive Subscale of the Cambridge Mental Disorders of the Elderly Examination and the Mini Mental State Examination at follow‐up. There was a significant decline in performance on the Digit Symbol Substitution Test in subjects who had evidence of T2 foci compared to the performance of subjects without T2 foci. This may indicate that the presence of T2 foci is correlated with subtle difficulties in learning and memory. © 1990 The American Geriatrics Society

引用

页码：1133 / 1138

页数：6

共 21 条

[1] INCIDENTAL SUBCORTICAL LESIONS IDENTIFIED ON MAGNETIC-RESONANCE-IMAGING IN THE ELDERLY .1. CORRELATION WITH AGE AND CEREBROVASCULAR RISK-FACTORS [J].