GENETIC ANALYSES OF CELL-MATRIX INTERACTIONS IN DEVELOPMENT

被引:53
作者
HYNES, RO [1 ]
机构
[1] MIT, CTR CANC RES, CAMBRIDGE, MA 02139 USA
关键词
D O I
10.1016/0959-437X(94)90074-D
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The extracellular matrix and its cell surface receptors are thought to be important in development. Recent applications of targeted mutagenesis in mice have begun to test hypotheses based on in vitro data and patterns of expression. 'Knockout' mutations of matrix molecules and integrins reveal complexities arising from multiple receptors and ligands.
引用
收藏
页码:569 / 574
页数:6
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