ALPHA,BETA-UNSATURATED CARBONYL-COMPOUNDS WITH STERICALLY PROTECTED CARBONYL GROUPS - ENFORCED A3 VERSUS A1 REACTIVITY

被引：42

作者：

SEEBACH, D

LOCHER, R

机构：

[1] Laboratorium Für Organische Chemie, Eidgenössischen Technischen Hochschule, Eth-Zentrum, CH-8092

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 12期

关键词：

D O I：

10.1002/anie.197909571

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A shift in the reactivity of α,β‐unsaturated carbonyl compounds can be accomplished by steric protection of the carbonyl group. Thus 1 reacts with organolithium exclusively at C‐3 to give Michael adducts 2 which can be cleaved to form carboxylic acid derivatives. (Figure Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany

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页码：957 / 958

页数：2

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