THE EFFECTS OF IVABRADINE AND OMEGA-3 POLYUNSATURATED FATTY ACIDS ON WHITE BLOOD CELLS COUNT AND ITS POPULATIONS IN PATIENTS WITH ISCHEMIC HEART FAILURE

被引：0
作者：
Fedorov, S. [1 ]
机构：
[1] Ivano Frankivsk Natl Med Univ, Ivano Frankivsk, Ukraine
来源：
PHARMACIA | 2014年 / 61卷 / 04期
关键词：
heart failure; white blood cells count; ivabradine; omega-3 polyunsaturated fatty acids;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The aim of this study was to investigate the possible influence of ivabradine and omega-3 polyunsaturated fatty acids on leukocyte' and its populations counts in patients with ischemic heart failure. 357 patients with ischemic HF and sinus rhythm were observed. Additional usage of omega-3 PUFA caused a WBC count decrease by 12.3% - 12.5% (p< 0.05) and neutrophil count by 8.3% - 9.6% ( p< 0.05). Thus,omega-3 polyunsaturated fatty acids have influence on elevated WBC (especially granulocytes) counts and showed anti-inflammatory effects. Further studies designed to investigate the influence of these medications on other inflammatory markers in heart failure are needed to determine new approach in prediction and prevention of heart failure.
引用
收藏
页码：18 / 21
页数：4
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