INDOMETHACIN TREATMENT IN AMPHOTERICIN-B INDUCED NEPHROGENIC DIABETES-INSIPIDUS

被引：1

作者：

HOHLER, T ^{[1
]}

TEUBER, G ^{[1
]}

WANITSCHKE, R ^{[1
]}

ZUMBUSCHENFELDE, KHM ^{[1
]}

机构：

[1] UNIV MAINZ,MED KLIN & POLIKLIN 1,D-55101 MAINZ,GERMANY

来源：

CLINICAL INVESTIGATOR | 1994年 / 72卷 / 10期

关键词：

DRUG-INDUCED DIABETES INSIPIDUS; AMPHOTERICIN B; INDOMETHACIN; PROSTAGLANDIN E(2);

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nephrogenic diabetes insipidus (NDI) is a serious side effect of various drugs. Elevated renal prostaglandin E(2) levels have been found in patients with lithium-induced NDI and have been implicated in the pathogenesis. We report the case of a patient who developed NDI following treatment with amphotericin B. Prostaglandin levels were elevated. Indomethacin had an antidiuretic effect and normalized prostaglandin levels.

引用

页码：769 / 771

页数：3

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