CORRELATION OF TIMI RISK SCORE WITH SEVERITY OF CORONARY ARTERY DISEASE BY CORONARY ANGIOGRAM IN PATIENTS WITH NON-ST-ELEVATION MYOCARDIAL INFARCTION

Objective: To determine the correlation of TIMI risk score with severity of coronary artery disease by coronary angiogram in patients with non-ST-elevation myocardial infarction (NSTEMI). Methodology: This cross-sectional study was conducted at Department of Cardiology, Jinnah Hospital, Lahore from 1st April 2016 to 30th September 2016. Patients presenting with non-ST-elevation myocardial infarction (NSTEMI) were enrolled and received standard medical therapy. Patients were risk stratified with TIMI risk scores as low, intermediate and high. Patients were evaluated with coronary angiograms to assess the extent of coronary artery disease (CAD). The severity of CAD evaluated on angiography was measured by GENSINI Score. Results: Total of 110 pateints were included in the study with 88 patients (80%) were below 60 years whereas 22 patients (20%) were either 60 years or more in age. About 75 patients (68.2%) were males. Mean TIMI score of patients was 4.68 +/- 1.33 ranged from 2 to 7. Mean GENSINI score of sampled population was 21.45 +/- 4.108 ranged from 11 to 30. Correlation between TIMI score and severity of CAD came out 0.47. It was also significant. Presence of diabetes, hypertension and gender had no significant effect on correlation. Conclusion: It is concluded that there is moderate correlation (r=0.47) between TIMI score & severity of CAD as measured by GENSINI score in our sampled population.