INTRAGENIC SUPPRESSION - STALKER, A RETROVIRUS-LIKE TRANSPOSABLE ELEMENT, CAN COMPENSATE FOR A DEFICIENCY AT THE CUT LOCUS OF DROSOPHILA-MELANOGASTER

A number of mutations at the cut locus were induced by non-precise exision of a silent P-element insertion which resulted in deletions at the regulatory region of the locus. Unexpectedly a reversion of one of these mutations was found, which appears as a result of insertion of Stalker (a retrovirus-like mobile element) near the 1.3 kb deletion. Thus an insertion of a retrovirus-like mobile element can suppress the deficiency at the regulatory region of a gene.