INTRAGENIC SUPPRESSION - STALKER, A RETROVIRUS-LIKE TRANSPOSABLE ELEMENT, CAN COMPENSATE FOR A DEFICIENCY AT THE CUT LOCUS OF DROSOPHILA-MELANOGASTER

被引:8
作者
MOGILA, VA
LADVISHENKO, AB
SIMONOVA, OB
GERASIMOVA, TI
机构
[1] Institute of Gene Biology, Academy of Sciences of the USSR, Moscow, 117908, Vavilov st.
关键词
D O I
10.1007/BF00133729
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A number of mutations at the cut locus were induced by non-precise exision of a silent P-element insertion which resulted in deletions at the regulatory region of the locus. Unexpectedly a reversion of one of these mutations was found, which appears as a result of insertion of Stalker (a retrovirus-like mobile element) near the 1.3 kb deletion. Thus an insertion of a retrovirus-like mobile element can suppress the deficiency at the regulatory region of a gene.
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页码:305 / 311
页数:7
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