MALIGNANT RHABDOID TUMOR OF SOFT-TISSUES - A CYTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY

被引：28

作者：

PEREZ, JS

PEREZGUILLERMO, M

BERNAL, AB

LOPEZ, TM

LOPEZ, FC

机构：

[1] Department of Cytopathology, Arrixaca University Hospital, Department of Pathology, Murcia Medical School, Murcia

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1992年 / 8卷 / 04期

关键词：

FINE-NEEDLE ASPIRATION CYTOLOGY; IMMUNOHISTOCHEMISTRY; HYALINE INCLUSION; CHILDHOOD ROUND-CELL TUMORS;

D O I：

10.1002/dc.2840080413

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

We describe the cytopathological and immunohistochemical features of a primary malignant rhaboid tumor (MRT) located in the left forehead region of an 8-mo-old female. The cardinal characteristics are hyaline cytoplasmic inclusions, rounded or bean-shaped nucleus, vesicular chromatin, central prominent nucleolus, and poorly defined cytoplasmic profile. Both the cytoplasm and the hyaline inclusion are vimentin and keratin positive, but negative with desmin, S-100 protein, neuron-specific enolase, (NSE) myoglobin, leukocyte common antigen (LCA), and alpha-1-antichymotrypsin. This immunohistochemical pattern, although not exclusive to MRT, is fairly typical of MRT, and when it is assessed in conjunction with cytopathological findings and clinical data permits a confident diagnosis of MRT We emphasize the utility of immunohistochemical techniques in making the differential diagnosis of MRT against other childhood round-cell tumors.

引用

页码：369 / 373

页数：5

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