A STUDY ON EFFECT OF LANATOSIDE C ON VENTRICULAR AUTOMATICITY IN MAN

被引:6
作者
EDHAG, O
ROSEN, A
机构
[1] Department of Medicine and Department of Clinical Physiology, Karolinska Instituter, Serafimerlasarettet, Stockholm
关键词
Artificial pacemaker; Digitalis; Electrocardiography; Heart; Heart block; Idioventricular rhythm; Lanatoside C; Ventricular automaticity;
D O I
10.3109/00365516909078084
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The effect of Lanatoside C on ventricular automaticity was studied in six patients with complete heart block and artificical pacemaker stimulation. A suppressive action of Lanatoside C on ventricular automaticity may be produced indirectly by diminishing an increased cardiac sympathetic outflow. However, the present observation of an unchanged sinus rate after the administration of Lanatoside C does not support such a mechanism. The possibility of a direct depressive effect of the drug on ventricular automaticity might therefore be considered. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:43 / &
相关论文
共 17 条
[1]  
Campbell M, 1944, BRIT HEART J, V6, P69
[2]   CHANGES IN VENTRICULAR AUTOMATICITY - DRUG INDUCED AND EXPOSED BY INTRACARDIAC ELECTRIC STIMULATION [J].
CASTELLANOS, A ;
LEMBERG, L ;
SOMMER, L ;
BERKOVITS, B .
SOUTHERN MEDICAL JOURNAL, 1965, 58 (12) :1517-+
[3]  
EDELIST A, 1963, CIRCULATION, V28, P715
[4]  
ETTINGER E, 1966, CIRCULATION S3, V33, P98
[5]  
GOODMAN L, 1965, DIGITALIS ALLIED ED, P665
[6]  
JOHANSSON BW, 1966, ACTA MED SCAND S180
[8]   MECHANISM OF DIGITALIS ACTION ON HEART [J].
KOCHWESER, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1967, 277 (08) :417-+
[9]   100 CASES OF TREATMENT FOR ADAMS-STOKES SYNDROME WITH PERMANENT INTRAVENOUS PACEMAKER [J].
LAGERGRE.H ;
JOHANSSO.L ;
LANDEGRE.J ;
EDHAG, O .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1965, 50 (05) :710-&
[10]   REAPPRAISAL OF DIGITALIS .I. DIGITALIS ACTION AT CELLULAR LEVEL [J].
LYON, AF ;
DEGRAFF, AC .
AMERICAN HEART JOURNAL, 1966, 72 (03) :414-&