THE BETA-SUBUNIT AND GAMMA-SUBUNIT OF GTP-BINDING PROTEINS ACTIVATE THE MUSCARINIC K+ CHANNEL IN HEART

被引：1037
作者：
LOGOTHETIS, DE
KURACHI, Y
GALPER, J
NEER, EJ
CLAPHAM, DE
机构：
[1] HARVARD UNIV,SCH MED,DEPT PHYSIOL & BIOPHYS,BOSTON,MA 02115
[2] UNIV TOKYO,DIV MED,DEPT INTERNAL MED 2,ANAT 2,TOKYO 113,JAPAN
[3] BRIGHAM & WOMENS HOSP,DEPT MED,DIV CARDIOVASC,BOSTON,MA 02115
来源：
NATURE | 1987年 / 325卷 / 6102期
关键词：
D O I：
10.1038/325321a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：321 / 326
页数：6
相关论文
共 31 条
[1]  
BIRNBAUMER L, 1985, PERTUSSIS TOXIN, P77
[2]  
BOKOCH GM, 1983, J BIOL CHEM, V258, P2072
[3]   GTP-BINDING PROTEINS - ONE MOLECULAR MACHINE CAN TRANSDUCE DIVERSE SIGNALS [J].
BOURNE, HR .
NATURE, 1986, 321 (6073) :814-816
[4]   UNCOUPLING OF CARDIAC MUSCARINIC AND BETA-ADRENERGIC RECEPTORS FROM ION CHANNELS BY A GUANINE-NUCLEOTIDE ANALOG [J].
BREITWIESER, GE ;
SZABO, G .
NATURE, 1985, 317 (6037) :538-540
[5]  
CLAPHAM D, HEART CELL CULTURE
[6]  
CODINA J, 1984, J BIOL CHEM, V259, P1408
[7]  
Colquhoun D., 1983, SINGLE CHANNEL RECOR, Vsecond, P191
[8]  
COTE TE, 1984, J BIOL CHEM, V259, P8693
[9]  
COTE TE, 1985, PERTUSSIS TOXIN, P129
[10]   IMPROVED PATCH-CLAMP TECHNIQUES FOR HIGH-RESOLUTION CURRENT RECORDING FROM CELLS AND CELL-FREE MEMBRANE PATCHES [J].
HAMILL, OP ;
MARTY, A ;
NEHER, E ;
SAKMANN, B ;
SIGWORTH, FJ .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1981, 391 (02) :85-100
1234