Measurement of Anticardiolipin Antibody in Patients with Acute Coronary Syndrome (ACS)

被引：0

作者：

Omran, M. T. Salehi ^{[1
]}

Mirzaei, F. ^{[1
]}

机构：

[1] Babol Univ Med Sci, Shaheed Beheshti Hosp, Dept Cardiol, Babol Sar, Iran

来源：

IRANIAN HEART JOURNAL | 2007年 / 8卷 / 03期

关键词：

anticardiolipin antibody; acute coronary syndrome; antiphospholipid syndrome; atherosclerosis; antiphospholipid antibody;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background- Elevated levels of anticardiolipin antibody may be associated with the high prevalence of coronary artery disease. In this study, we measured the anticardiolipin antibody level in patients with acute coronary syndrome (ACS) and a control group. Methods- 63 patients with ACS (unstable angina - U/A, and acute myocardial infarction - AMI) presenting to our department were studied. Diagnosis of ACS was confirmed by clinical exam, history, ECG and cardiac enzyme determinations. Anticardiolipin antibody level was measured with the ELISA method in 63 patients with ACS and 130 healthy controls matched for sex and age, and samples were analyzed using SPSS and t-test. Results- The mean age of the patients and control group were 61.59 and 51.27 years, respectively. Mean anticardiolipin antibody level in patients with ACS was higher than that in the control group (P = 0.038). In men with ACS, the mean anticardiolipin antibody level was also higher than that in the control group (P= 0.002). In patients above 45 years of age, the mean anticardiolipin antibody level was higher than that in the control group (P = 0.012). Conclusion- Our study shows that there are higher anticardiolipin antibody levels in patients with ACS compared to controls. Thus, the evaluation of anticardiolipin antibody level in patients with ACS is necessary

引用

页码：41 / 43

页数：3

共 14 条

[1]

Antman EM, 2005, HARRISONS PRINCIPLES, V16, P1448

[2]

ASHERSON RA, 1989, Q J MED, V73, P1103

[3]

Fuster V, 2001, HEART, V1, P1373

[4]

Gaeta G, ANTICARDIOLIPIN ANTI

[5]

Harris EN, 2001, KLIPPLE, V7

[6]

Kitagawa Yasuhisa, 2005, Rinsho Shinkeigaku, V45, P852

[7] Medical progress: The antiphospholipid syndrome. [J].

Levine, JS ;

Branch, DW ;

Rauch, J .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (10) :752-763

[8]

LIBBY P, 2005, HARRISONS PRINCIPLES, P1425

[9]

Libby P., 2005, HARRISONS PRINCIPLES, VII, P1432

[10] Thromboembolic risk in patients with high titre anticardiolipin and multiple antiphospholipid antibodies [J].

Neville, C ;

Rauch, J ;

Kassis, J ;

Chang, ER ;

Joseph, L ;

Le Comte, M ;

Fortin, PR .

THROMBOSIS AND HAEMOSTASIS, 2003, 90 (01) :108-115

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