ANALYSIS OF FRAGRANCE COMPOUNDS IN BLOOD-SAMPLES OF MICE BY GAS-CHROMATOGRAPHY, MASS-SPECTROMETRY, GC/FTIR AND GC/AES AFTER INHALATION OF SANDALWOOD OIL

被引:28
作者
JIROVETZ, L [1 ]
BUCHBAUER, G [1 ]
JAGER, W [1 ]
WOIDICH, A [1 ]
NIKIFOROV, A [1 ]
机构
[1] UNIV VIENNA,INST ORGAN CHEM,A-1090 VIENNA,AUSTRIA
关键词
D O I
10.1002/bmc.1130060307
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
After inhalation experiments with sandalwood oil and the pure fragrance compounds coumarin and alpha-terpineol, substances were detected and measured in the blood samples of test animals (mice) using gas chromatography/mass spectrometry (GC/MS) (MID) in connection with GC/FTIR (SWC), GC/AES (carbon and oxygen trace) and flame ionization detection/gas chromatography. Using tiglinic acid benzyl ester as the internal standard the following concentrations in serum could be found: alpha-santalol 6.1 ng/mL, beta-santalol 5.3 ng/mL and alpha-santalene 0.5 ng/mL. In separate inhalation experiments with coumarin and with alpha-terpineol the corresponding concentrations were 7.7 ng/mL and 6.9 ng/mL, respectively.
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页码:133 / 134
页数:2
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