SUPPRESSION OF MALIGNANCY BY CELL FUSION

被引：567

作者：

HARRIS, H

MILLER, OJ

KLEIN, G

WORST, P

TACHIBANA, T

机构：

[1] Department of Tumor Biology, Karolinska Institutet

来源：

NATURE | 1969年 / 223卷 / 5204期

关键词：

D O I：

10.1038/223363a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Malignancy can be suppressed when malignant cells are fused with certain non-malignant ones. The hybrid cells derived from such fusions give rise to segregants in which a loss of chromosomes is associated with reversion to malignancy. The expression of histo-compatibility antigens can also be suppressed when cells bearing these antigens are fused with others that express them poorly. © 1969 Nature Publishing Group.

引用

页码：363 / +

页数：1

共 27 条

[1]

BARSKI G, 1962, JNCI-J NATL CANCER I, V28, P801

[2]

BURDETTE WJ, 1966, VIRUSES INDUCING ED, P323

[3] PROPERTIES OF HYBRIDS BETWEEN POLYOMA-TRANSFORMED AND NORMAL MOUSE CELLS [J].